Personally I wouldn't even use Vanish to hang my Christmas decorations up!
I use 4lb Rapala Titanium Braid, far more limp than fireline and better on knots. 4lb Yamatoyo leader is the best I have found, and thats after using just about all the major fluoro leaders on the market.
The other thing that helps when fishing light is good quality rods and reels. I use a 1000FB Stella, and custom rods. The last thing you need is a sticky drag or rod that cant handle the work.