No reason why they wouldn't work, although I wouldnt be using a jighead, just use a normal hook and run them on the top hook.
I've used big plastics rigged on weedless hooks with some success for Jewies off the beach.
Works on the same principal as a surf popper we use for salmon and more often than not they'll hit the popper instead of the bait.
Never hurts to try something different. I'd also be putting some artificial scent on them if you were going to fish them with this method rather than the traditional cast and retrieve